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results with Examination of human urine samples indicates that human UGT1A3 and UGT2B7 would be the predominant isoforms responsible for producing the foremost urinary metabolites of JWH-018 and JWH-073 (Chimalakonda et al., 2011b). It is crucial to spotlight that Despite the fact that these isoforms are present in large ranges within the liver, Th